Human bone marrow synthesised in lab

>> Tuesday, December 23, 2008

Artificial bone marrow that can continuously make red and white blood cells has been synthesised in a lab for the first time. This could lead to simpler pharmaceutical drug testing, closer study of immune system defects and a continuous supply of blood for transfusions.

To determine whether the substance behaves like real bone marrow, the scientists implanted it in mice with immune deficiencies. They produced human immune cells and blood vessels grew through the substance.

Cancer-fighting chemotherapy drugs can strongly suppress bone marrow function, leaving the body more susceptible to infection.

The new artificial marrow could allow researchers to test how a new drug at certain potencies would affect bone marrow function, said Nicholas Kotov, co-author of the study and professor in University of Michigan departments of chemical and bio-medical engineering.
"This could assist in drug development and avoid severe side effects before human drug trials," he said.

The substance grows on a 3-D scaffold that mimics the tissues supporting bone marrow in the body, Kotov and Joan Nichols, professor at the University of Texas, collaborated on many aspects of the project.

"This is the first successful artificial bone marrow," Kotov said. "It has two of the essential functions of bone marrow. It can replicate blood stem cells and produce B cells. The latter are the key immune cells producing antibodies that are important to fighting many diseases."
Blood stem cells give rise to blood as well as several other types of cells. B cells, a type of white blood cell, battle colds, bacterial infections, and other foreign or abnormal cells including some cancers.

Bone marrow is a complicated organ to replicate, Kotov said. Vital to the success of this new development is the 3-D scaffold on which the artificial marrow grows. This lattice had to have a high number of precisely-sized pores to stimulate cellular interaction.
The scaffolds are made of a transparent polymer that nutrients can easily pass through. To create the scaffolds, scientists moulded the polymer with tiny spheres ordered like billiard balls. Then, they dissolved the spheres to leave the perfect geometry of pores in the scaffold.
The scaffolds were then seeded with bone marrow stromal cells and osteoblasts, another type of bone marrow cell, said a Michigan university release. The findings were published online in Biomaterials.
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Procelain Veneers

>> Tuesday, December 9, 2008

Porcelain veneers are a beautiful way to correct stained, chipped, or crooked teeth. By placing glass-like ceramic porcelain on the surface of teeth, dentists can provide patients with bright, straight, and natural looking smiles.
Porcelain veneers can change the appearance of existing tooth but Dental veneer only done by an experienced dentist, and the Porcelain used were natural and strong.veneers can bring about a positive change to your physical appearance when placed by an experienced and well trained cosmetic dentist.
it can help for improving an color and shape of your teeth and, this is also used to removing the small gaps between teeths.it looks as a natural as a normal health teeths looks like.
for more information about Porcelain veneers visit http://www.creatingsmiles.ca

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Cosmetic Dentist in city like Mississauga

>> Friday, December 5, 2008

Cosmetic dentistry is all about creating a gorgeous smile on your face. As we all are aware that one’s features play a very significant part our lives. Most of the individuals feel that smile is the first and foremost thing which anyone notices on a person and that smile takes much of the part in having any personal and professional decisions. Veneers are simply a thin layer or coverings that are used on teeth to accurate and imperfection that may be noticeable to the bare eye. So if an individuals who have certain imperfections on the teeth that are noticeable to the bare eyes, they must take steps to accurate the state by means of veneers.

If we have spaces in our teeth, or if our tooth is vaguely bust, stained or in a bad form dentists can use veneers to accurate the state. If we occur to be residing in a city like Mississauga, then we are very lucky as we can have access to the most excellent dentists that are operating in the city if we occur to suffer from any type of dental imperfection.

Veneers Mississauga is ideal means of accurate different kinds of dental imperfections that an individual may have. If we occur to be affliction from any type of dental imperfection, the first thing which we need to do is to look for appointment with a dentist. Keep in mind it is eternity better for us to see the dentist before the situation becomes complexity for treatment.

After checking the patient’s condition dentist might ask them to undergo any treatment which a patient should be sure to do that.

Relating veneers on teeth is a very simple chore for the dentist. The major cause for this is the truth that this function mostly does not need to give any type of anesthesia to the patient. Porcelain veneers, a type of veneers can be efficiently utilized to mask any staining which may be present on our teeth. Veneers are very much resistant next to all types of discoloration that are formed by certain food substances. So after relating veneers on our teeth we can securely take food substances like tea, coffee and wine without too much of a constraint. However we must make sure that just since we have applied veneers does not signify that we can indulge in eating all these food substances.

Vast progressions have been made in the field of dentistry and in current times approximately any kind of dental imperfection can be cured without any difficulty. In reality there is no ground for us to not work towards perfecting your smile. Through the utilization of veneers and the other curing measures available everything can be treated properly. If we take appropriate care of our teeth and pursue certain basic rules for having vigorous teeth we would never meet any type of dental difficulties. After all this is our teeth and we must make certain that they are in high-quality state and help us to guide a healthy life.For more information about creatingsmilesca please visit http://www.creatingsmiles.ca

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